Urticarial vasculitis - Urticarial Vaskulit
https://en.wikipedia.org/wiki/Urticarial_vasculitis
☆ Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan. relevance score : -100.0%
References
Urticarial vasculitis 34222586 NIH
Urticarial vasculitis - kamdan-kam uchraydigan holat bo'lib, u uzoq davom etadigan yoki takrorlanadigan epizodlar bilan tavsiflanadi. Uning teri belgilari surunkali kovaklar kabi bo'lishi mumkin bo'lsa-da, ular o'ziga xosdir, chunki uyamalar kamida 24 soat davomida yopishadi va so'ngandan keyin qora dog'lar paydo bo'lishiga olib kelishi mumkin. Ko'pincha noma'lum sabab bo'lsa-da, ba'zida ba'zi dori-darmonlar, infektsiyalar, otoimmün kasalliklar, qon kasalliklari yoki saraton kasalliklari sabab bo'lishi mumkin. Ba'zi tadqiqotlar buni hatto COVID-19 va H1N1 grippi bilan bog'lagan. Shuningdek, u mushaklar, buyraklar, o'pka, oshqozon va ko'z kabi tananing boshqa qismlariga ham ta'sir qilishi mumkin. To'qimalarni tekshirishning ma'lum bir turi tashxisni tasdiqlashi mumkin bo'lsa-da, bu har doim ham zarur emas. Davolash odatda antibiotiklar, dapson, kolxitsin yoki engilroq holatlarda gidroksiklorokin bilan boshlanadi. Keyinchalik og'ir holatlarda metotreksat yoki kortikosteroidlar kabi immunitet tizimini bostiradigan dorilar kerak bo'lishi mumkin. Yaqinda biologik terapiya (rituximab, omalizumab, interleukin-1 inhibitors) og'ir holatlar uchun va'da berdi.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Faropenem-induced urticarial vasculitis - Case reports 3358092835 yoshli erkak 15 kun davomida ikkala son va oyoqlarda yorqin qizil, og‘riqli toshmalar, bo‘g‘imlardagi og‘riqlar bilan keldi. Toshma paydo bo'lishidan bir hafta oldin siydik yo'llari infektsiyasi bo'lgan. Uning terisida son va oyoqlarning ikkala tomonida bir nechta nozik, halqasimon, qisman oqartiruvchi, qizil rangli plitalar paydo bo'ldi. Unga uyqusiz antigistamin (feksofenadin) bilan bir hafta davomida og'iz orqali prednizolon (kuniga 40 mg) berildi. Bir hafta ichida barcha toshmalar butunlay yo'qoldi. Keyingi 6 oy davomida muntazam tekshiruvlar davomida toshmalar yo'q edi.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
○ Davolash ― OTC dori vositalari
Agar sizda isitma (tana haroratining ko'tarilishi) bo'lsa, imkon qadar tezroq shifokorga murojaat qilishingizni tavsiya qilamiz.
Shubhali dori to'xtatilishi kerak. (masalan, antibiotiklar, steroid bo'lmagan yallig'lanishga qarshi dorilar)
Qichishish uchun setirizin yoki loratadin kabi og'iz antigistaminlari.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Birjadan tashqari steroid moylari past kuch uchun samarasiz bo'lishi mumkin. Yaxshilanishni ko'rish uchun bir haftadan ko'proq vaqt davomida qo'llash kerak.
#Hydrocortisone ointment